Thymosin b10 human, rat

Thymosin Beta-10 (Human/Rat sequence, Ac-Ala-Asp-Lys-Pro-Asp-Met-Gly-Glu-Ile-Ala-Ser-Phe-Asp-Lys-Ala-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Thr-Leu-Pro-Thr-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Arg-Ser-Glu-Ile-Ser-OH, TFA salt) is a 43-residue member of the beta-thymosin family, the most abundant class of G-actin-monomer-sequestering peptides in mammalian cytoplasm. Like its more widely studied relative Thymosin Beta-4 (the parent sequence behind TB-500 research material), Beta-10 forms a 1:1 complex with monomeric G-actin, buffering the free-actin pool and shifting the equilibrium between filamentous (F-actin) and monomeric (G-actin) states that governs cytoskeletal remodeling, cell motility, and mitotic spindle dynamics.

Potential Research Applications: Actin-sequestering / cytoskeletal dynamics research, comparing Beta-10's affinity and structural behavior against Thymosin Beta-4 in reconstituted actin systems Developmental and neuronal migration research — beta-thymosin expression has been studied as a marker of neuronal differentiation and migratory capacity in developing tissue Intrinsically disordered protein (IDP) structural biology — beta-thymosins fold into a transient helical conformation only upon binding actin, making them a model system for IDP-target interactions Comparative expression studies across cell and tumor lines, where beta-thymosin family members are frequently profiled together

Platform Pricing Data (live, updated continuously): Peptides.SO currently tracks 1 supplier offering Thymosin Beta-10 (Human/Rat) at $159.50/mg. With only a single listed reference point, this is not yet a competitive multi-supplier field — treat the current price as a single data point rather than a market range, and check this page for new listings as coverage grows.

Cited Research: Yu FX, et al. Effects of thymosin beta 4 and thymosin beta 10 on actin structures in living cells. Cell Motil Cytoskeleton. 1994. PubMed PMID: 8194107. Xue B, Leyrat C, Grimes JM, Robinson RC. Actin-Induced Structure in the Beta-Thymosin Family of Intrinsically Disordered Proteins. Vitam Horm. 2016. PubMed PMID: 27450730.

For laboratory research use only. Not for human or veterinary use, diagnosis, treatment, cure, or prevention of any disease. THIS PRODUCT IS NOT FOR HUMAN CONSUMPTION.